Which supplement is commonly used to support cholesterol management?

• A. Garlic
• B. Ginkgo biloba
• C. St. John's Wort
• D. Melatonin

Answer: (A)

Supplements can influence lipid levels, and garlic is commonly used to support cholesterol management because studies have shown modest reductions in total cholesterol and LDL cholesterol with its use. The active compounds in garlic, such as organosulfur constituents like allicin, are thought to affect cholesterol biosynthesis and oxidation pathways, and may also have antioxidant effects that contribute to improved lipid profiles. Importantly, the impact tends to be small compared to prescription statins, so garlic is best viewed as an adjunctive, lifestyle-support option rather than a replacement for standard therapy.

The other options don’t target cholesterol in a meaningful way. Ginkgo biloba is studied mainly for cognitive function and circulatory concerns, not lipid levels. St. John’s Wort mainly affects mood and drug metabolism through enzyme induction, which can alter the levels of many medications. Melatonin is used for sleep regulation and circadian rhythm disorders, with little relevance to cholesterol management.